According to a study published in International Journal of Food Sciences:
"The researchers concluded that the best way to cook mushrooms while still preserving their nutritional properties is to grill or microwave them, as the fried and boiled mushrooms showed significantly less antioxidant activity. The fried mushrooms in particular revealed a severe loss in protein and carbohydrate content, but an increase in fat."
http://time.com/4787928/cook-mushrooms-science/
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